Combo DNA Ancestry Test, mtDNA + Y-DNA STR

The Combo DNA Ancestry Test examines both maternally inherited mitochondrial DNA (mtDNA) and paternal Y-DNA STR markers in one ancestry-focused kit. It traces direct maternal and paternal lines, offers Standard, Advanced, and Premium testing levels, and provides online results for family-history and genealogy research. Because the test includes Y-DNA analysis, it is intended for male test takers; a female seeking paternal-line information can test an eligible direct male-line relative.

Key Features

• Combines mitochondrial DNA and Y-DNA STR testing
• Traces direct maternal and paternal lineages
• Standard, Advanced, and Premium testing levels
• Access to ancestry databases for DNA matching and genealogy research
• Includes a mouth-swab sample collection process and online results
• Designed for male test takers because Y-DNA analysis requires a Y chromosome

Test Options

• Standard: 20 Y-STR markers and mtDNA HVR1 sequence
• Advanced: 44 Y-STR markers and mtDNA HVR1 plus HVR2 sequence
• Premium: 101 Y-STR markers and the full mtDNA genome sequence, including HVR1, HVR2, and the coding region

Customers can begin with the Standard level and use the available upgrade path if they later want a higher-resolution test option.

What the Test Examines

mtDNA: Mitochondrial DNA is inherited through the maternal line and can be used to study direct maternal ancestry. Depending on the selected level, the test examines HVR1, HVR1 plus HVR2, or the complete mitochondrial genome.

Y-DNA: Y-DNA is passed through the paternal line. Y-STR testing compares repeated DNA markers on the Y chromosome, allowing compatible profiles to be compared for paternal-line matches and estimated time to most recent common ancestor, or TMRCA.

Included Ancestry Databases

• DNA Reunion Database: Search for potential family-line connections and biological relatives
• Indigenous DNA Database: Compare DNA profiles with participating Indigenous groups in the database
• DNA Haplogroups Database: Explore deep ancestry and haplogroup information reaching back more than 100,000 years
• Famous DNA Database: Compare DNA with notable historical figures included in the database, such as Marie Antoinette, Genghis Khan, Nicholas Copernicus, and King Richard III

How It Works

1. Order the Combo DNA Ancestry Test kit online
2. Collect the sample using the included mouth swab
3. Mail the sample to the laboratory in the provided return envelope
4. Receive the test results online

Ideal For

This combo test is suited to genealogy research, family-history projects, ancestry comparisons, and customers who want maternal and paternal lineage information from one kit. Review the marker and sequencing differences between Standard, Advanced, and Premium before ordering so you can choose the level that fits your research goals.

Frequently Asked Questions

Who can take the Combo DNA Ancestry Test?
The test is intended for male test takers because it includes Y-DNA analysis. A female who wants to investigate her paternal line can have an eligible direct male-line relative, such as her father, brother, paternal uncle, or qualifying paternal male cousin, take the test. The mtDNA portion traces the direct maternal line.

What sample does the kit use?
The kit uses a mouth, or cheek, swab. Collect the sample according to the included instructions and return it to the laboratory in the provided envelope.

What is the difference between Standard, Advanced, and Premium?
The options differ in the number of Y-STR markers and the mtDNA regions sequenced. Standard includes 20 Y-STR markers and mtDNA HVR1, Advanced includes 44 Y-STR markers and mtDNA HVR1 plus HVR2, and Premium includes 101 Y-STR markers and the full mtDNA genome sequence.

How are results delivered?
After the laboratory receives and processes the sample, results are provided online. Review the kit documentation for current processing details and access instructions.