{"product_id":"dna-celiac-disease-test-at-home-hla-genetic-risk-screening-kit","title":"DNA Celiac Disease Test, At-Home HLA Genetic Risk Screening Kit","description":"\u003ch2\u003eDNA Celiac Disease Test – Know Your Genetic Risk for Gluten Sensitivity\u003c\/h2\u003e\n\u003cp\u003eThe DNA Celiac Disease Test is an at-home genetic screening kit that determines whether you carry HLA gene variants associated with an increased risk of celiac disease. Almost all people with celiac disease carry at least one genetic risk allele — find out your status with a simple, painless cheek swab from the comfort of home. Results are delivered within 1–3 business days after the laboratory receives your sample.\u003c\/p\u003e\n\u003ch3\u003eKey Benefits\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eScreens for HLA variants (DQ2 and DQ8) associated with celiac disease risk\u003c\/li\u003e\n\u003cli\u003eA negative result rules out celiac disease for life\u003c\/li\u003e\n\u003cli\u003eAccurate even if you are already on a gluten-free diet\u003c\/li\u003e\n\u003cli\u003ePainless buccal (cheek swab) sample collection — no needles or clinic visit\u003c\/li\u003e\n\u003cli\u003eResults in 1–3 business days after laboratory receipt\u003c\/li\u003e\n\u003cli\u003e24\/7 online test status tracking\u003c\/li\u003e\n\u003cli\u003ePrivate, confidential, and secure\u003c\/li\u003e\n\u003cli\u003eNo age limit\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWhat Is Celiac Disease?\u003c\/h3\u003e\n\u003cp\u003eCeliac disease is an autoimmune disorder in which the immune system mistakenly attacks the lining of the small intestine in response to gluten — a protein found in wheat, rye, barley, and oats. Over time, this immune reaction damages the intestinal lining and can lead to serious nutritional deficiencies and health complications. Importantly, a gluten-free diet is \u003cem\u003enot\u003c\/em\u003e required before testing, as this test analyzes your DNA rather than antibody levels.\u003c\/p\u003e\n\u003ch3\u003eThe Genetics\u003c\/h3\u003e\n\u003cp\u003eAlmost all people with celiac disease carry at least one genetic risk allele in their \u003cem\u003eHLA\u003c\/em\u003e genes. This test detects nucleotide changes in three celiac-associated alleles of the \u003cem\u003eHLA-DQA1\u003c\/em\u003e and \u003cem\u003eHLA-DQB1\u003c\/em\u003e genes (\u003cem\u003eHLA-DQA1*05, HLA-DQB1*02, HLA-DQB1*0302\u003c\/em\u003e). These variants can pair to form proteins known as DQ2 and DQ8, which indicate varying levels of celiac disease risk.\u003c\/p\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eGenotype (celiac-associated alleles present)\u003c\/th\u003e\n\u003cth\u003eCeliac Disease Risk\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDQ2 and DQ8\u003c\/td\u003e\n\u003ctd\u003e1 in 7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDQ2 and Homozygous \u003cem\u003eHLA-DQB1*02\u003c\/em\u003e\n\u003c\/td\u003e\n\u003ctd\u003e1 in 10\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDQ2 and DQ2\u003c\/td\u003e\n\u003ctd\u003e1 in 10\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDQ8 and DQ8\u003c\/td\u003e\n\u003ctd\u003e1 in 12\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDQ8 and \u003cem\u003eHLA-DQB1*02\u003c\/em\u003e\n\u003c\/td\u003e\n\u003ctd\u003e1 in 24\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHomozygous \u003cem\u003eHLA-DQB1*02\u003c\/em\u003e\n\u003c\/td\u003e\n\u003ctd\u003e1 in 26\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDQ2\u003c\/td\u003e\n\u003ctd\u003e1 in 35\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDQ8\u003c\/td\u003e\n\u003ctd\u003e1 in 89\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHeterozygous \u003cem\u003eHLA-DQB1*02\u003c\/em\u003e\n\u003c\/td\u003e\n\u003ctd\u003e1 in 210\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cem\u003eHLA-DQA1*05\u003c\/em\u003e only\u003c\/td\u003e\n\u003ctd\u003e1 in 1,842\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eNo HLA celiac-associated alleles detected\u003c\/td\u003e\n\u003ctd\u003eNot at risk — less than 1 in 2,518\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch3\u003eCommon Symptoms of Celiac Disease\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBloating and flatulence\u003c\/li\u003e\n\u003cli\u003eConstipation and\/or diarrhea\u003c\/li\u003e\n\u003cli\u003eNausea and vomiting\u003c\/li\u003e\n\u003cli\u003eAppetite changes\u003c\/li\u003e\n\u003cli\u003ePale or bloody stools\u003c\/li\u003e\n\u003cli\u003eFatigue and nutritional deficiencies\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eFrequently Asked Questions\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eDo I need to be eating gluten before taking this test?\u003c\/strong\u003e\u003cbr\u003eNo. Unlike antibody blood tests for celiac disease, this DNA test analyzes your genetic makeup rather than your immune response. Your results will be accurate regardless of whether you are currently following a gluten-free diet.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat does a negative result mean?\u003c\/strong\u003e\u003cbr\u003eA negative result means no HLA celiac-associated alleles were detected. This rules out celiac disease with a very high degree of certainty, as fewer than 1 in 2,518 people without these alleles develop the condition.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes a positive result mean I have celiac disease?\u003c\/strong\u003e\u003cbr\u003eNot necessarily. Carrying HLA risk alleles increases your genetic susceptibility but does not confirm a diagnosis. Many people carry these variants without ever developing celiac disease. A positive result should be discussed with your physician, who may recommend further testing.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow is the DNA sample collected?\u003c\/strong\u003e\u003cbr\u003eDNA is collected using a painless buccal (cheek) swab. Simply rub the swab gently inside your mouth against your cheek for 15 seconds. No needles, blood draws, or clinic visits are required.\u003c\/p\u003e\n\u003ch3\u003eHow It Works\u003c\/h3\u003e\n\u003col\u003e\n\u003cli\u003eOrder your kit online and receive it at home.\u003c\/li\u003e\n\u003cli\u003eCollect your DNA sample using the painless cheek swab provided.\u003c\/li\u003e\n\u003cli\u003eMail your sample to the lab in the prepaid return envelope.\u003c\/li\u003e\n\u003cli\u003eReceive your results online within 1–3 business days.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"Genovate","offers":[{"title":"Default Title","offer_id":8839328170038,"sku":"Celiac Disease Test","price":249.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1443\/4772\/products\/genovate-diet-fitness-default-title-dna-celiac-disease-test-at-home-hla-genetic-risk-screening-kit-845853884470.jpg?v=1788637094","url":"https:\/\/www.precisionlabworks.com\/products\/dna-celiac-disease-test-at-home-hla-genetic-risk-screening-kit","provider":"Precision Lab Works","version":"1.0","type":"link"}