Does your face turn red when you drink? Do you experience severe hangovers from just one drink? If you answered yes, you may be alcohol intolerant. Find out your risk of alcohol intolerance with this DNA test.
The majority of the alcohol (aka the chemical ethanol) that enter our body is cleared via a two-step process involving two enzymes.
In the first step of alcohol metabolism, alcohol dehydrogenase (ADH) converts ethanol to acetaldehyde. Acetaldehyde is a toxic chemical. But is usually short-lived, because it is quickly converted to acetate by aldehyde dehydrogenase (ALDH) in the second step of alcohol metabolism. The end product acetate is easily broken down to carbon dioxide and water.
People with genetic variants in the alcohol metabolism pathway either generate acetaldehyde too quickly, or are unable to eliminate it fast enough. This results in the dangerous build up of acetaldehyde in the body, even when moderate amounts of alcohol is consumed.
A simple mouth swab is all we need to find out whether you have inherited DNA changes that affect your ability to metabolize alcohol, and may increase your risk of serious health complications.
People with genetic variants in the alcohol metabolism pathway either generate acetaldehyde too quickly, or are unable to eliminate it fast enough. This results in a dangerous build up of toxic acetaldehyde in the body, even when moderate amounts of alcohol are consumed.
GENETIC VARIANTS IDENTIFIED IN THIS TEST:
HEALTH RISK FOR HETEROZYGOTES:
Heterozygotes are people who inherit two different versions of a particular gene. ADH1B, ADH1C and ALDH2 genes have a cumulative affect. For example,
Individuals with two slow ALDH2 alleles have:
– Zero detectable ALDH enzyme activity
– Severe side effects
Heterozygotes for ALDH2 (one fast allele and one slow allele) have:
– 30-50% reduction in ALDH enzyme activity
– Moderate side effects
– An increased risk of health complications
SYMPTOMS OF ALCOHOL INTOLERANCE:
If you are genetically susceptible, every drink you consume is harming your health
How It Works
Step 1: Order test kit online
Step 2: Collect DNA sample using a painless mouth swab, and mail to the lab in the provided return envelope
Step 3: Receive your results online
NOTE: Please provide your email address for reporting results.
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