FREE STANDARD SHIPPING ON ALL PRODUCTS WITHIN THE 48 STATES.
Couldn't load pickup availability
The DNA Caffeine Sensitivity Test reveals whether you are a fast or slow caffeine metabolizer based on genetic variants in your CYP1A2 gene, helping you understand how caffeine affects your health and whether cutting back may reduce your risk of heart problems or hypertension. Sample collection is quick, painless, and done entirely at home using a buccal cheek swab.
Not all of us are equally affected by caffeine. Caffeine sensitivity depends on how long it stays in your body. Some people are fast caffeine metabolizers and clear it quickly, while slow metabolizers take much longer. The longer caffeine stays in circulation, the higher the risk of cardiovascular problems. By drinking more than 3 cups of coffee per day, a slow metabolizer may increase their risk of a heart attack by 2 to 4 times and hypertension by 3 times.
Close to 95% of the caffeine in the body is broken down by the CYP1A2 enzyme. There are two common genetic variants, a fast metabolizer variant and a slow metabolizer variant. The slow genetic variant is associated with lower levels of the CYP1A2 enzyme and a slower rate of caffeine breakdown. Reduced caffeine consumption is generally recommended for slow metabolizers to lower cardiovascular risk.
What does it mean to be a slow caffeine metabolizer?
Slow metabolizers carry a genetic variant of the CYP1A2 enzyme that breaks down caffeine more slowly. This means caffeine stays in their system longer, increasing the risk of heart attack and hypertension with high caffeine intake.
Do I need to stop drinking coffee before the test?
No. This test analyzes your DNA, not caffeine levels in your blood. You can collect your sample at any time regardless of recent caffeine consumption.
How is the sample collected?
DNA is collected using a painless buccal (cheek) swab. Simply rub the swab inside your mouth against your cheek for 15 seconds. No needles or clinic visits are required.
How long does it take to receive results?
Results are delivered online within 1 to 3 business days after the laboratory receives your sample. You will be notified by email when your results are ready.