Cardiovascular Health Risk DNA Test – At-Home Heart Gene Screening Kit

Cardiovascular Health Risk DNA Test – Know Your Heart Health Genetics

The Cardiovascular Health Risk DNA Test reveals whether you carry inherited genetic variants that affect your risk of heart disease. Unlike the single-gene APOE test, this comprehensive panel screens multiple genes linked to cholesterol levels, triglycerides, inflammation markers, and cell proliferation — giving you a fuller picture of your cardiovascular genetic profile. All from a simple, painless cheek swab at home.

Key Benefits

• Comprehensive multi-gene panel covering HDL, LDL, triglycerides, CRP, and lipoprotein(a)
• Identifies both risk-increasing and protective genetic variants
• Understand your inherited cardiovascular risk and take targeted action
• Painless buccal (cheek swab) sample collection — no needles or clinic visit
• Results in 1–3 business days after laboratory receipt
• 24/7 online test status tracking
• Private, confidential, and secure
• No age limit

About Cardiovascular Disease

Cardiovascular disease (CVD) encompasses a broad spectrum of disorders — many involving narrowed or blocked blood vessels — leading to chest pain (angina), heart attacks, and strokes. CVD is the leading cause of death worldwide, accounting for over 30% of all deaths. While lifestyle factors like physical inactivity, poor diet, and smoking increase risk, certain inherited genetic variants can also significantly predispose individuals to heart disease — independent of lifestyle choices.

Genes Tested & Their Effects

• Reduced “good” HDL-cholesterol: ANGPTL4, APOA5, FADS1, GALNT2, HNF4A, LIPG, MMAB
• Elevated “good” HDL-cholesterol: CETP, LCAT, LIPC, LPL
• Reduced “bad” LDL-cholesterol: APOB, FADS1, LDLR, NCAN, PCSK9, SORT1, SUGP1
• Elevated “bad” LDL-cholesterol: HMGCR, HNF1A, TRIB1
• Elevated lipoprotein(a): LPA
• Elevated C-reactive protein (CRP): CRP, GCKR
• Elevated triglycerides: APOA5, FADS1, GALNT2, GCKR, NOS3, TRIB1
• Reduced triglycerides: ANGPTL3, LPL, MLXIPL, NCAN
• Decreased control of cell proliferation: 9p21

Key Cardiovascular Risk Factors Explained

• Cholesterol (HDL & LDL): HDL (“good”) cholesterol helps remove LDL (“bad”) cholesterol from arteries. Reduced HDL or excess LDL leads to arterial buildup, narrowing blood vessels and increasing heart attack and stroke risk.
• Triglycerides: Fats stored in the body after digestion. Chronically elevated triglycerides contribute to obesity, atherosclerosis, and heart disease.
• C-reactive protein (CRP): A liver-produced inflammation marker. Elevated CRP is associated with increased cardiovascular disease risk.
• Lipoprotein(a): A lipoprotein similar to LDL. Elevated levels significantly increase the risk of CVD and are largely genetically determined.

How It Works

1. Order your kit online and receive it at home
2. Register and activate your kit online, then collect your DNA sample using the painless cheek swab provided
3. Mail your sample to the lab in the prepaid return envelope
4. Receive your results securely online within 1–3 business days