DNA Celiac Disease Test – At-Home HLA Genetic Risk Screening Kit

DNA Celiac Disease Test – Know Your Genetic Risk for Gluten Sensitivity

The DNA Celiac Disease Test is an at-home genetic screening kit that determines whether you carry HLA gene variants associated with an increased risk of celiac disease. Almost all people with celiac disease carry at least one genetic risk allele — find out your status with a simple, painless cheek swab from the comfort of home. Results are delivered within 1–3 business days after the laboratory receives your sample.

Key Benefits

• Screens for HLA variants (DQ2 and DQ8) associated with celiac disease risk
• A negative result rules out celiac disease for life
• Accurate even if you are already on a gluten-free diet
• Painless buccal (cheek swab) sample collection — no needles or clinic visit
• Results in 1–3 business days after laboratory receipt
• 24/7 online test status tracking
• Private, confidential, and secure
• No age limit

What Is Celiac Disease?

Celiac disease is an autoimmune disorder in which the immune system mistakenly attacks the lining of the small intestine in response to gluten — a protein found in wheat, rye, barley, and oats. Over time, this immune reaction damages the intestinal lining and can lead to serious nutritional deficiencies and health complications. Importantly, a gluten-free diet is not required before testing, as this test analyzes your DNA rather than antibody levels.

The Genetics

Almost all people with celiac disease carry at least one genetic risk allele in their HLA genes. This test detects nucleotide changes in three celiac-associated alleles of the HLA-DQA1 and HLA-DQB1 genes (HLA-DQA1*05, HLA-DQB1*02, HLA-DQB1*0302). These variants can pair to form proteins known as DQ2 and DQ8, which indicate varying levels of celiac disease risk.

Common Symptoms of Celiac Disease

• Bloating and flatulence
• Constipation and/or diarrhea
• Nausea and vomiting
• Appetite changes
• Pale or bloody stools
• Fatigue and nutritional deficiencies

How It Works

1. Order your kit online and receive it at home
2. Collect your DNA sample using the painless cheek swab provided
3. Mail your sample to the lab in the prepaid return envelope
4. Receive your results online within 1–3 business days