DNA Lactose Intolerance Test

The DNA Lactose Intolerance Test identifies whether you carry genetic variants associated with lactose intolerance or lactase persistence, using an analysis of five common changes in the MCM6 gene. Almost 65% of people worldwide are lactose intolerant to some degree — this simple, painless cheek swab test helps you find out if your digestive symptoms may have a genetic cause. Results are delivered privately and confidentially online.

DNA Lactose Intolerance Test, Key Features

• Analyzes five common genetic variants in the MCM6 gene linked to lactose intolerance
• Differentiates between lactose intolerance and lactase persistence
• Painless buccal (cheek) swab sample collection, no needles or clinic visit required
• 100% private and confidential online results

Lactose Intolerance vs Lactase Persistence

People who are lactose intolerant cannot digest and absorb the milk sugar lactose, because they produce only low levels of the lactase enzyme. This causes digestive symptoms such as gas, bloating, and diarrhea when dairy products are consumed. Lactase persistence is the opposite — people who are lactase persistent produce the lactase enzyme throughout their lives and can continue consuming dairy into adulthood without symptoms.

The Genetics Behind Lactose Intolerance

Genetic variation is the strongest predictor of lactose intolerance and lactase persistence. The MCM6 gene encodes a protein that controls the production of other proteins, including lactase encoded by the nearby LCT gene. People with at least one of the five tested MCM6 variants are unlikely to suffer from lactose intolerance. Those who do not carry any of these variants have an increased risk of lactose intolerance.

The likelihood of lactose intolerance varies significantly by ethnicity. Lactose intolerance affects approximately 90% of Asian Americans, 70% of African Americans, 95 to 100% of Native Americans, and 50% of Mexican Americans. In contrast, fewer than 25% of Caucasians and only about 5% of people of Northern European ancestry are lactose intolerant, reflecting a long history of dairy as a dietary staple.

Symptoms of Lactose Intolerance

• Bloating and abdominal distension
• Flatulence and gurgling sounds from the abdomen
• Diarrhea
• Nausea or vomiting
• Abdominal pain or cramps

How It Works

1. Order your DNA Lactose Intolerance Test kit online and receive it at home
2. Register and activate your kit, then collect your DNA sample using the painless cheek swab provided
3. Mail your sample to the lab in the prepaid return envelope
4. Receive your results securely online

Frequently Asked Questions

What does it mean if I test positive for lactose intolerance risk?
A result indicating increased lactose intolerance risk means you do not carry the MCM6 gene variants associated with lactase persistence. This suggests your body may produce lower levels of the lactase enzyme, making it harder to digest dairy. Discuss your results with a healthcare provider or registered dietitian for personalized dietary guidance.

Can I still eat dairy if I have a high-risk result?
Many people with lactose intolerance can tolerate small amounts of dairy or choose lactase enzyme supplements to aid digestion. A registered dietitian can help you determine the right approach based on your results and symptoms.

How is the sample collected?
DNA is collected using a painless buccal (cheek) swab. Simply rub the swab inside your mouth against your cheek for 15 seconds. No needles, blood draws, or clinic visits are required.

How long does it take to receive results?
Results are delivered securely online within 1 to 3 business days after the laboratory receives your sample. You will be notified by email when your results are ready.